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Extubation failure

Reintubation within 24 h 30 min before first confirmed extubation

Potential use: ventilator management. We prioritize calibrated risk and the tradeoff between reintubation risk and unnecessary delay. High-risk alerts use scores at or above the cutoff; the prespecified extubation action is below it.

Retrospective benchmark results do not establish benefit in clinical care.

Models

External AUROC is the mean AUROC across eligible external sites, weighted by test hospitalizations. MIMIC-CLIF remains a public reference. Full-report selections do not change this summary.

Task definition and ranking methods

Endpoint: reintubation within 24 hours of the first confirmed extubation. Prediction time: 30 minutes before that extubation. Extubations followed by death within 24 hours, or without a complete 24-hour observation, are excluded unless reintubation occurs within that interval.

Endpoint
Reintubation within 24 h
Prediction time
30 min before first confirmed extubation
Reporting mode
Episodic episodic
Task threshold
0.10
High-risk alarm rule
Score ≥0.10
Decision-curve action
Extubation, score <0.10
Potential action
ventilator management evaluated retrospectively; not a clinical recommendation
Task ID
extubation_failure_24h
Task class
intervention
Temporal pattern
episode
Prediction unit
one-per-stay
Task type
binary
Label column
label_extubation_failure_24h

The external summary weights each eligible site by test hospitalizations, never daily prediction rows. Scores and intervals in Summary use two decimals; ordering uses the available source precision before display rounding. Full report retains more precision. Formal ranks are pending verification of identical task versions, evaluation protocols, eligible site sets and per-site test partitions across submissions. A change requires a new ranking version and reference-model reevaluation. Exact ties must share a rank once comparability is verified. The current exports do not establish all these conditions. Only per-site confidence intervals are shown in Summary; averaging site confidence limits does not establish an interval for the ranking score.

Summary policy: flair-manuscript-2026-10-18. A missing required external estimate leaves the overall summary unavailable; remaining site reports stay accessible.

Which result each site publishes: the site a model was trained on publishes its local arm; every other site publishes external validation. A site's own-data result is never presented as external validation.

Intervals: 95% percentile-bootstrap intervals (500 replicates specified) resample hospitalizations at each site. They are not adjusted for multiplicity across tasks, sites, or thresholds, no formal hypothesis tests are performed, and they should not be used to infer statistically significant differences between sites.

Validation tags: external validation means a model is evaluated on participating external site data. Local validation means the model is evaluated on the held-out test split of the site it was trained on.

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